Downloads: 138
Research Paper | Hematology | Volume 4 Issue 8, August 2015 | Pages: 735 - 738 | India
To Test the Accuracy of Platelet Count, as Corrected by Citrate Anticoagulant in EDTA Induced Pseudo-Thrombocytopenia
Abstract: Background EDTA- induced pseudothrombocytopenia (EDTA-PTCP) is a common laboratory phenomenon with a prevalence ranging from 0.1-2 % in hospitalized patients to 15-17 % in outpatients evaluated for isolated thrombocytopenia. (EDTA-PTCP) is falsely low platelet count due to antibodies directed against glycoprotein (gp) IIb-IIIa complex leading to agglutination. Misinterpretation of artificial low platelet count lead to unnecessary transfusion of platelets increasing the risk of associated morbidity. Methodology & Results- A Total of 100 Cases of EDTA induced Pseudo-thrombocytopenia as corrected by Citrate anticoagulant is studied. The PLT Count by Abotts Cell DYN Ruby using EDTA as anticoagulant is ( 55 25.9) & citrate anticoagulant is ( 217.8 61.16) x103/mm. Manual platelet count = 222 58.7 x103/mm. P value
Keywords: platelet aggregation, pseudothrombocytopenia, anticoagulation, EDTA, citrate, agglutination
How to Cite?: Mirza Asif Baig, "To Test the Accuracy of Platelet Count, as Corrected by Citrate Anticoagulant in EDTA Induced Pseudo-Thrombocytopenia", Volume 4 Issue 8, August 2015, International Journal of Science and Research (IJSR), Pages: 735-738, https://www.ijsr.net/getabstract.php?paperid=SUB157394, DOI: https://dx.doi.org/10.21275/SUB157394