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Original Research | Pathology | Volume 15 Issue 7, July 2026 | Pages: 1835 - 1842 | India
Seroprevalence of HIV, Hepatitis B, and Hepatitis C among Blood Donors at a Tertiary Care Center
Abstract: Background: Transfusion-transmissible infections (TTIs), particularly Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV), remain major challenges to blood safety worldwide. Regular surveillance of these infections among blood donors is essential to ensure safe transfusion practices and to monitor disease trends in the community. Objectives: 1) To analyze the seroprevalence of transfusion-transmitted infections (TTIs), including HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV), among blood donors. 2) To assess the prevalence of transfusion-transmitted infections (TTIs), namely HIV, HBV, and HCV, among male and female blood donors. 3) To determine the incidence of transfusion-transmitted infections (TTIs), including HIV, HBV, and HCV, among blood donors aged 18-60 years. Materials and Methods: A prospective observational study was conducted in the Department of Pathology, Blood Bank, GMERS Medical College, Gandhinagar, Gujarat, from July 2023 to February 2025. A total of 11,111 eligible blood donors were included after obtaining informed consent. Donor demographic details, blood group, donor type, and relevant clinical information were recorded using a standardized donor registration form. All donated blood units were screened for HIV, Hepatitis B surface antigen (HBsAg), and HCV using standard serological assays as per national blood transfusion guidelines. Data were entered in Microsoft Excel and analyzed using SPSS software. Descriptive statistics were used to summarize the data, and the Chi-square test was applied to determine statistical significance, with a p-value
Keywords: Blood donors, Transfusion-transmissible infections, HIV, Hepatitis B virus, Hepatitis C virus, Seroprevalence, Blood safety, Voluntary blood donation
How to Cite?: Dr. Shivangi Chaudhari, Dr. Gautam Chauhan, Dr. Meeta Parikh, "Seroprevalence of HIV, Hepatitis B, and Hepatitis C among Blood Donors at a Tertiary Care Center", Volume 15 Issue 7, July 2026, International Journal of Science and Research (IJSR), Pages: 1835-1842, https://www.ijsr.net/getabstract.php?paperid=SR26721164416, DOI: https://dx.doi.org/10.21275/SR26721164416