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Original Research | Obstetrics and Gynecology | Volume 15 Issue 4, April 2026 | Pages: 1746 - 1750 | India
Does Serum Vitamin D Level Have an Impact on Semen Parameters?
Abstract: Background: Vitamin D receptors located on the head and mid piece of a sperm suggest a possible role of vitamin D in male fertility. This study evaluated the association between serum vitamin D levels and semen parameters in subfertile men. Methods: In this prospective observational study, after applying inclusion and exclusion criteria, 75 subfertile men were included and they underwent semen analysis according to WHO 2021 criteria and serum vitamin D assessment by ELISA assay. Participants were categorized as vitamin D deficient or sufficient and semen parameters were compared. The semen parameters of the males belonging to vitamin D sufficient versus vitamin D deficient group were expressed in terms of Mean ? standard deviation. Student t -test was employed as appropriate, p-value<0.05 was considered significant. Results: Vitamin D deficient men had significantly lower sperm concentration, total sperm count, progressive motility, morphology and total motile sperm count compared with vitamin D sufficient men, while age, BMI and semen volume showed no significant association. The p-value of total sperm motility, the primary outcome of this study was 0.002 and was statistically significant. The secondary outcomes like total motility of sperms and morphology were also clinically significant. Conclusion: Adequate serum vitamin D levels were associated with better semen quality. Larger prospective and interventional studies are needed to clarify causality.
Keywords: Vitamin D, Male infertility, Semen quality, Subfertility, Spermatogenesis, Sperm motility
How to Cite?: Priya M, Kundavi K. M, Rashmi G. V, Geetha V, Geovin Ranji, Yamini Asokan, Hema Nivedha K. R, Sandhya Devarajan, "Does Serum Vitamin D Level Have an Impact on Semen Parameters?", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 1746-1750, https://www.ijsr.net/getabstract.php?paperid=SR26425235036, DOI: https://dx.dx.doi.org/10.21275/SR26425235036