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Research Paper | Microbiology | Volume 15 Issue 4, April 2026 | Pages: 1575 - 1580 | India
Identification, Speciation and Antibiogram of Urinary Pathogens from Hospitalized Patients at Tertiary Care Hospital
Abstract: Background: Urinary tract infections (UTIs) are a major cause of morbidity in hospitalized patients and are increasingly associated with multidrug-resistant (MDR) organisms. Institution-specific data are essential for guiding empiric therapy. Objectives: To identify urinary pathogens and determine their antibiotic susceptibility patterns in admitted patients with suspected UTIs. Methods: This prospective observational study was conducted over six months, processing 421 urine samples using standard microbiological techniques. Identification was done by culture and biochemical methods, and antibiotic susceptibility testing was performed using the Kirby-Bauer method and VITEK system as per CLSI guidelines. Data were analyzed using descriptive statistics and Chi-square test. Results: Significant growth was observed in 63% of samples. Escherichia coli (52%) was the predominant isolate, followed by Klebsiella pneumoniae (21%), Pseudomonas aeruginosa (8%), Acinetobacter spp. (7%), Enterococcus spp. (8%), and Candida spp. (4%). High resistance to fluoroquinolones and cephalosporins was noted among Gram-negative isolates, while sensitivity to nitrofurantoin, carbapenems, and colistin remained effective. Over 50% of isolates were MDR, with ESBL production in 42% of E. coli and 48% of Klebsiella. Conclusion: Rising MDR and ESBL rates highlight the need for regular antibiograms and antimicrobial stewardship.
Keywords: Urinary tract infection, Uropathogens, Antibiogram, Multidrug resistance, ESBL
How to Cite?: Dr. Md Aqib Ali N, Dr. Narayan Shrihari, Dr. Mariraj Jeer, Dr. Kumudini TS, Dr. Haafiza Begum, "Identification, Speciation and Antibiogram of Urinary Pathogens from Hospitalized Patients at Tertiary Care Hospital", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 1575-1580, https://www.ijsr.net/getabstract.php?paperid=SR26424103840, DOI: https://dx.dx.doi.org/10.21275/SR26424103840