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Review Papers | Biomedical Sciences | Volume 15 Issue 3, March 2026 | Pages: 114 - 120 | India
Transport of Nanoparticles in Targeted Drug Delivery System
Abstract: Nanoparticle-based drug delivery has emerged as a promising and evolving field in developing advanced diagnostics and therapeutics for blood flow-related disorders. A nanofluid consists of a colloidal suspension of nanoparticles, typically ranging from 10 to 100 nanometer (nm), dispersed in conventional carrier fluids such as water, oil, or even biological media like blood. Compared to conventional drug delivery systems, nanoparticles offer several advantages, including enhanced specificity, improved stability, superior drug-loading capacity, and the potential for controlled or sustained release. Both organic and inorganic nanoparticles have been widely investigated as drug carriers due to their excellent biocompatibility with tissues and cells, nanoscale size, reduced toxicity, and ability to achieve prolonged therapeutic effects. Moreover, using nanoparticles as drug delivery agents helps mitigate resistance and reduces the impact of blood flow obstruction or coagulation associated with stenosis. Targeted drug delivery aims to ensure that an appropriate amount of the therapeutic agent reaches its intended site of action. By carefully designing such delivery systems, it becomes possible to use lower doses while minimizing unwanted side effects, leading to better patient compliance. The main goal of focused drug transport is to achieve a safe and efficient interaction of the drug with the specific diseased tissue. Nanoparticle-based drug delivery plays a crucial role in treating complex conditions such as cancer, disorders involving the blood-brain barrier, and cardiovascular diseases, where precise targeting is essential to enhance therapeutic efficacy and minimize damage to healthy tissues. Mathematical modelling serves as a valuable tool for analyzing the intricate dynamics of blood flow in arterial stenosis, thereby contributing to the optimization of clinical treatments and advancements in biomedical engineering.
Keywords: Nanoparticles, Blood Flow, Stenosis, Non-Newtonian Fluid, Targeted Drug Delivery, Cancer, Mathematical Modelling
How to Cite?: Nivedita Gupta, Pallavi Gautam, "Transport of Nanoparticles in Targeted Drug Delivery System", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 114-120, https://www.ijsr.net/getabstract.php?paperid=SR26226181516, DOI: https://dx.dx.doi.org/10.21275/SR26226181516