Wound Healing: A Narrative Review of Cellular Mechanisms, Regulatory Factors, and Clinical Implications

Dr. Parvati Huded

Abstract: Wound healing is a highly regulated and dynamic biological process that restores tissue integrity following injury. It involves a complex interplay of cellular elements, extracellular matrix components, cytokines, and growth factors, progressing through overlapping phases of hemostasis, inflammation, proliferation, and maturation. Disruptions in any phase may result in impaired healing or abnormal scar formation such as hypertrophic scars and keloids. Systemic conditions, including diabetes mellitus and smoking, further compromise wound repair. This narrative review summarizes the current understanding of the biological mechanisms underlying wound healing, highlights factors influencing normal and abnormal repair, and discusses emerging therapeutic approaches.

Keywords: wound healing process, tissue repair, scar formation, healing disorders, emerging therapies

How to Cite?: Dr. Parvati Huded, "Wound Healing: A Narrative Review of Cellular Mechanisms, Regulatory Factors, and Clinical Implications", Volume 15 Issue 1, January 2026, International Journal of Science and Research (IJSR), Pages: 1672-1674, https://www.ijsr.net/getabstract.php?paperid=SR26128222251, DOI: https://dx.doi.org/10.21275/SR26128222251