Comparative Analysis of TURP and Open Prostatectomy: Experience from a Tertiary Care Institution

Darshan Rathi, Amol Kamble, Shashank Sharma

Abstract: Introduction: Benign prostatic hyperplasia (BPH) is a common condition in aging men, often requiring surgical intervention for large prostate volumes causing significant symptoms or complications. Open prostatectomy (OP) and transurethral resection of the prostate (TURP) are widely used surgical options, yet comparative data in Indian tertiary care settings remain limited. Methods: This retrospective comparative study included 50 men aged ?50 years with BPH and prostate volume >80 grams. Patients underwent either OP (n=25) or TURP (n=25). Preoperative, intraoperative, and postoperative parameters, including International Prostate Symptom Score (IPSS), were analysed over a 3-month follow-up. Results: Baseline characteristics were comparable between groups. TURP had shorter operative time (68.3 vs 92.7 min, p < 0.001), less blood loss (180 vs 295 mL, p < 0.001), shorter catheterization (3.2 vs 6.7 days, p < 0.001), and fewer transfusions (8% vs 24%, p <0.05). Open surgery removed more tissue (81.3 vs 62.1 g, p < 0.001) and required longer hospital stay (8.2 vs 4.4 days, p < 0.001). Both groups showed marked IPSS improvement at 3 months (TURP: 7.2, Open: 8.8). Complication rates, including urinary tract infections and transient incontinence, did not differ significantly. Both groups experienced significant and sustained IPSS improvement at 3 months, with TURP showing marginally better symptomatic relief. Conclusion: TURP offers a less invasive alternative to OP with faster recovery and comparable symptomatic outcomes for large prostate management. OP remains effective for extensive tissue removal but with higher morbidity. These findings support individualized surgical choice considering patient and resource factors.

Keywords: Benign prostatic hyperplasia, Open prostatectomy, Transurethral resection of the prostate, prostatomegaly

How to Cite?: Darshan Rathi, Amol Kamble, Shashank Sharma, "Comparative Analysis of TURP and Open Prostatectomy: Experience from a Tertiary Care Institution", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 1193-1196, https://www.ijsr.net/getabstract.php?paperid=SR25822002159, DOI: https://dx.doi.org/10.21275/SR25822002159