Erase the haze: Resolution of Immediate Corneal Stromal Haze Following CXL: A Case Report

Ankeeta Thali, Prabhu Vijayaraghavan

Abstract: Corneal collagen cross-linking (CXL) is a standard treatment to halt the progression of keratoconus. While generally safe, early postoperative complications such as stromal haze can significantly affect visual outcomes. We report a case of immediate-onset stromal haze developing one month after accelerated CXL in a 16-year-old male with keratoconus. The patient underwent uneventful CXL in the left eye, following which he developed significant central stromal haze accompanied by corneal flattening. Initiation of aggressive topical corticosteroid therapy with 1% prednisolone acetate resulted in a marked reduction in haze, with corresponding clinical improvement. This case underscores the importance of close postoperative monitoring and highlights the efficacy of early, intensive corticosteroid therapy in managing acute stromal haze following CXL. Timely intervention may optimize visual recovery and minimize long-term sequelae. Further studies are warranted to establish standardized treatment protocols for such early complications.

Keywords: Corneal collagen cross-linking, Keratoconus, Stromal haze, Corticosteroids

How to Cite?: Ankeeta Thali, Prabhu Vijayaraghavan, "Erase the haze: Resolution of Immediate Corneal Stromal Haze Following CXL: A Case Report", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 1321-1323, https://www.ijsr.net/getabstract.php?paperid=SR25822001426, DOI: https://dx.doi.org/10.21275/SR25822001426