Using the HACOR Score to Predict Non-Invasive Ventilation Failure in Acute Hypoxemic Respiratory Failure

Dr. Pujan Acharya, Dr. Praveen Bharti, Dr. Sandeep Garg, Dr. Sunita Aggarwal, Dr. Abhishek Gupta, Dr. Manidipa Mondal, Dr. Muskan Garg, Dr. Ravada Hemanth Sai Sri Harsha

Abstract: Acute hypoxemic respiratory failure (AHRF) is a leading cause of morbidity, and timely prediction of non-invasive ventilation (NIV) failure is crucial to prevent delays in escalation of care. This prospective observational study included 50 AHRF patients who received NIV and were classified after 48 hours as either success or failure based on clinical outcomes. The HACOR score?based on heart rate, pH, GCS, oxygenation, and respiratory rate?was assessed at initiation and after one hour. After one hour, the HACOR score significantly decreased in the success group and increased in the failure group. A HACOR score of 7 or more strongly predicted NIV failure, demonstrating high sensitivity (78.26%) and specificity (96.30%). The findings support the HACOR score as a reliable early indicator of NIV failure, enabling clinicians to make timely decisions that may reduce mortality.

Keywords: Noninvasive Ventilation, Respiratory Failure, Hypoxemia, HACOR score

How to Cite?: Dr. Pujan Acharya, Dr. Praveen Bharti, Dr. Sandeep Garg, Dr. Sunita Aggarwal, Dr. Abhishek Gupta, Dr. Manidipa Mondal, Dr. Muskan Garg, Dr. Ravada Hemanth Sai Sri Harsha, "Using the HACOR Score to Predict Non-Invasive Ventilation Failure in Acute Hypoxemic Respiratory Failure", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 1079-1084, https://www.ijsr.net/getabstract.php?paperid=SR25820001048, DOI: https://dx.doi.org/10.21275/SR25820001048