Adjunctive Therapies in Maxillary Expansion: Bridging Orthopedic Force and Bone Preservation

Renuka Devasath, Priyank Rai

Abstract: Maxillary expansion (ME) is an established treatment for transverse maxillary deficiencies but can cause undesirable effects such as buccal bone loss, dental tipping, and periodontal compromise. This review evaluates current adjunctive approaches aimed at enhancing skeletal outcomes and minimizing complications in rapid maxillary expansion techniques, including RME, MARPE, and SARPE. Biological methods (platelet-rich plasma, injectable platelet-rich fibrin, bioactive glass/fibrin glue, krill oil), surgical and mechanical aids (micro-osteoperforations, corticotomies, piezosurgery), and pharmacologic agents (strontium ranelate, rhBMP-2) have demonstrated potential to accelerate bone regeneration, improve expansion stability, and reduce relapse. Reported mechanisms include stimulation of osteoblastic activity, angiogenesis promotion, reduction of skeletal resistance, and modulation of bone turnover. Integrating these adjunctive measures into ME procedures may enhance skeletal expansion efficiency, preserve periodontal health, and optimize patient outcomes.

Keywords: maxillary expansion, adjunctive therapy, bone regeneration, i-PRF, LLLT, micro-osteoperforations

How to Cite?: Renuka Devasath, Priyank Rai, "Adjunctive Therapies in Maxillary Expansion: Bridging Orthopedic Force and Bone Preservation", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 912-917, https://www.ijsr.net/getabstract.php?paperid=SR25813151407, DOI: https://dx.doi.org/10.21275/SR25813151407