Role of Low-Dose Aspirin in the Prevention of Pre-eclampsia: Current Guidelines, Evidence, and Implementation Challenges

Dr. Manish

Abstract: Pre-eclampsia remains a major cause of maternal and perinatal morbidity and mortality globally, particularly in low- and middle-income countries. Low-dose aspirin (LDA) has emerged as a key preventive strategy due to its antiplatelet and anti-inflammatory properties. This review summarizes the pathophysiology of pre-eclampsia, the pharmacological rationale for aspirin uses, and the evidence supporting its efficacy. It also reviews current global and national guidelines on LDA use, optimal dosing strategies, and barriers to implementation in clinical settings, particularly in resource-limited environments. Effective implementation of LDA for pre-eclampsia prevention requires provider training, community awareness, and health system strengthening.

Keywords: Low-dose aspirin, Pre-eclampsia, Antenatal care, Hypertensive disorders of pregnancy, ACOG guidelines, ISSHP, Maternal morbidity

How to Cite?: Dr. Manish, "Role of Low-Dose Aspirin in the Prevention of Pre-eclampsia: Current Guidelines, Evidence, and Implementation Challenges", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 116-117, https://www.ijsr.net/getabstract.php?paperid=SR25802162337, DOI: https://dx.doi.org/10.21275/SR25802162337