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Experimental Result Paper | Medical Surgical | Volume 14 Issue 7, July 2025 | Pages: 1870 - 1872 | India
Prevalence, Risk Factors, and Clinical Impact of Multidrug-Resistant Organisms in Diabetic Foot Ulcers
Abstract: Background: Diabetic foot ulcers (DFUs) present a major complication of diabetes in India, with multidrug-resistant organisms (MDROs) escalating therapeutic challenges. Methods: An 18-month prospective observational study at ASRAM hospital enrolled 150 diabetic patients with foot lesions. Demographics, clinical data, and microbiology were analyzed using Chi-square, Student?s t-test, and multivariate logistic regression. Results: MDROs were detected in 68% of infected ulcers and accounted for 56.8% of all isolates. Polymicrobial infections occurred in 60.66% of cases, with gram-negative rods predominating (69.89%). The most frequent isolates were, 1) Escherichia coli (21.9%), 2) Staphylococcus aureus (18.6%), 3) Pseudomonas aeruginosa (18.2%). Recurrent ulcers (OR = 3.32) and higher Wagner?s grades (OR = 13.34) independently predicted MDRO infection. MDRO presence prolonged hospital stay (12.36 vs. 7.64 days; p
Keywords: diabetic foot ulcers, multidrug-resistant organisms, hospital stay and amputation, antibiotic resistance, polymicrobial infections
How to Cite?: Dr. P. Udaya Sri, Dr. Madala Sambasivarao, Dr. Suhas, Dr. N. V. Ramu Garikipudi, "Prevalence, Risk Factors, and Clinical Impact of Multidrug-Resistant Organisms in Diabetic Foot Ulcers", Volume 14 Issue 7, July 2025, International Journal of Science and Research (IJSR), Pages: 1870-1872, https://www.ijsr.net/getabstract.php?paperid=SR25730164233, DOI: https://dx.doi.org/10.21275/SR25730164233