A Study of Intra-Operative Difficulties in Relation to Clinical, Radiological and Biochemical Parameters in Laparoscopic Cholecystectomy

Dr. Ramendra Singh Rajawat, Dr. Madhubala Gaur, Dr. Bhaskar Kumar

Abstract: Background: Laparoscopic cholecystectomy (LC) has revolutionized the treatment of gallbladder diseases, offering a minimally invasive alternative to open cholecystectomy. Commonly indicated for conditions like cholecystitis and cholelithiasis. Clinical, radiological, and biochemical predictors play a crucial role in anticipating intraoperative difficulties and planning the surgical approach effectively. Aim and Objectives: The aim of this study is to explore intra-operative difficulties in relation to clinical, radiological, and biochemical parameters in laparoscopic cholecystectomy. The objectives include identifying clinical predictors of difficult LC, determining radiological predictors, assessing biochemical markers, comparing these factors with intra-operative difficulties. Methodology: This prospective interventional study was conducted at GS Medical College and Hospital, Pilkhuwa, Uttar Pradesh, India, over 15 to 18 months, involving 260 patients with cholelithiasis. Preoperative assessments included clinical evaluation, ultrasonography, and biochemical tests. Intra-operative findings and postoperative outcomes were meticulously recorded, with statistical analyses performed using SPSS version 25. Results: The study identified several predictors of intraoperative difficulty: a high BMI, previous abdominal surgeries, and abnormal ultrasonographic findings like a thickened gallbladder wall. Biochemical markers such as elevated liver enzymes also correlated with increased surgical complexity. Approximately 13.1% of LCs required conversion to open cholecystectomy due to unforeseen complications. Conclusion: The study confirmed that a thorough preoperative evaluation using clinical, radiological, and biochemical parameters can significantly anticipate and potentially mitigate intra-operative difficulties in laparoscopic cholecystectomy. These findings underscore the importance of a multidimensional assessment approach to enhance the safety and efficacy of LC.

Keywords: Cholelithiasis, Lap cholecystectomy, Surgery, Hospital

How to Cite?: Dr. Ramendra Singh Rajawat, Dr. Madhubala Gaur, Dr. Bhaskar Kumar, "A Study of Intra-Operative Difficulties in Relation to Clinical, Radiological and Biochemical Parameters in Laparoscopic Cholecystectomy", Volume 14 Issue 7, July 2025, International Journal of Science and Research (IJSR), Pages: 1654-1659, https://www.ijsr.net/getabstract.php?paperid=SR25725145204, DOI: https://dx.doi.org/10.21275/SR25725145204