Right Atrial Mass Lesion Discovered Following a Pathological Fracture: A Rare Presentation of Evolving Plasma Cell Neoplasm

Dr. Rathod Sowjanya, Dr. Katti Alekhya, Dr. Ade Kranthi Kumar, Dr. K Ravinder Reddy

Abstract: This case report describes a rare and evolving presentation of a plasma cell neoplasm in a 57-year-old female who initially presented with a solitary pathological tibial fracture and no prior history of multiple myeloma. Biopsy of the fracture-associated soft tissue mass confirmed plasmacytoma. Subsequent PET-CT and echocardiography revealed a right atrial mass. Initial serum electrophoresis showed no monoclonal band, but a later repeat confirmed an M- protein spike, supporting evolving multiple myeloma. The atrial mass regressed following radiotherapy but recurred after systemic chemotherapy, indicating aggressive extramedullary behaviour. This case highlights the importance of comprehensive evaluation in patients presenting with isolated bone lesions.

Keywords: Monoclonal antibodies, Multiple myeloma, Hypergammaglobulinemia, PET CT, Extramedullary plasmacytoma, Radiosensitive

How to Cite?: Dr. Rathod Sowjanya, Dr. Katti Alekhya, Dr. Ade Kranthi Kumar, Dr. K Ravinder Reddy, "Right Atrial Mass Lesion Discovered Following a Pathological Fracture: A Rare Presentation of Evolving Plasma Cell Neoplasm", Volume 14 Issue 7, July 2025, International Journal of Science and Research (IJSR), Pages: 661-664, https://www.ijsr.net/getabstract.php?paperid=SR25708100716, DOI: https://dx.doi.org/10.21275/SR25708100716