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Research Paper | Obstetrics and Gynecology | Volume 13 Issue 11, November 2024 | Pages: 42 - 45 | India
An Observational Study to Assess Thyroid Function Tests in First Trimester of Pregnancy
Abstract: Introduction: Miscarriage is a common occurrence in early pregnancy, defined as the loss of a nonviable intrauterine pregnancy within the first 12 weeks. Various maternal and fetal factors contribute to miscarriage, with maternal thyroid dysfunction playing a significant role. Thyroid disorders, particularly hypothyroidism, are prevalent in reproductive - age women and can lead to complications such as miscarriage, preterm birth, and fetal developmental issues. Objective: This study aims to assess the relationship between thyroid function and the risk of miscarriage by comparing thyroid hormone levels, including thyroid - stimulating hormone (TSH), T3, T4, and thyroid peroxidase antibodies (TPO - Ab), in women with early pregnancy loss versus those with viable pregnancies. Materials and Methods: A comparative observational study was conducted at the Department of Obstetrics and Gynecology, SMS Medical College, Jaipur, over one year, starting in November 2022. The study included 50 cases of women with first - trimester miscarriage and 50 controls with viable pregnancies. Thyroid function tests, including serum TSH, T3, T4, and TPO - Ab levels, were performed. Continuous variables were analyzed using an unpaired t - test, and categorical variables were analyzed using the chi - square or Fisher exact test, with a p - value
Keywords: Miscarriage, thyroid dysfunction, hypothyroidism, TSH, pregnancy, thyroid peroxidase antibodies
How to Cite?: Dr. Parul Sanwaria, Dr. Reena Pant, Dr. Aparna Sharma, Dr. Priyanka Singh, "An Observational Study to Assess Thyroid Function Tests in First Trimester of Pregnancy", Volume 13 Issue 11, November 2024, International Journal of Science and Research (IJSR), Pages: 42-45, https://www.ijsr.net/getabstract.php?paperid=SR241025120102, DOI: https://dx.doi.org/10.21275/SR241025120102