International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Medicine | India | Volume 12 Issue 6, June 2023 | Rating: 4.9 / 10


A Study to Assess the Proportion of Hypocortisolemia among Patients Admitted in Medical Intensive Care Unit in a Tertiary Care Hospital in Central Kerala

Merlin Elizabath Thomas | Geeta Panicker


Abstract: Introduction: Hypocortisolemia is a common complication that we come across in critically ill patients. Hence earlier diagnosis and adequate identification of this complication is warranted for planning early intervention. Methods: A cross sectional study was conducted among patients admitted in medical ICU under the Department of General Medicine, Amala Institute of Medical Sciences, Thrissur for a period of one year from March 2021 to February 2022. Consecutive consenting 231 patients were included in the study. Random serum cortisol level was assessed within 24 hours of admission to medical ICU. Patients with random serum cortisol level < 15?g/dl were considered to have hypocortisolemia, those with value between 15?g/dl - 34?g/dl were considered as normal and those patients with cortisol level > 34?g/dl were considered to have hypercortisolemia. Q - SOFA scoring was performed to assess the severity of illness. The requirement of vasopressors among the study population was noted. Patients were followed until the time of discharge from or death in medical ICU. Results: The proportion of hypocortisolemia in patients admitted to medical intensive care unit was 31.4%. The critically ill patients amongst the study population were found to have a significant association with low cortisol levels. Conclusion: Our study concluded that the proportion of hypocortisolemia among patients admitted in ICU was 31.4% with a male preponderance. Critically ill patients and those requiring a longer hospital stay were found to have a significant association with hypocortisolemia.


Keywords: hypocortisolemia, critical illness, Q - SOFA


Edition: Volume 12 Issue 6, June 2023,


Pages: 602 - 607


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