A Case Report of Systemic Lupus Erythematosus with Secondary Sjogren's Syndrome

Dr. A Harischandra Prasad, Dr. Shubham Sabne, Dr. Ravindra Varma, Dr. Jagruti Palav, Dr. Rajarathinum Raja, Dr. Sachin Bangar, Dr. Sandeep Holkar, Dr. A Harischandra Prasad

Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease in which organs and cells undergo damage initially mediated by tissue-binding auto antibodies and immune complexes. Most of the patients are women of childbearing age. SLE is 5.5-6.5 times more prevalent in women than men Sjogren's is also an Autoimmune disease characterized by lymphocytic infiltration of exocrine glands resulting in Xerostomia, Dry eyes and profound B cell hyperactivity. Females are more affected than males in this condition with a ratio (Female: Male) of 10-20: 1. With advancement in diagnostic modalities there has been a drastic change in understanding the disease pathology and to find treatment for better outcome for the patients.

Keywords: SLE, systemic lupus erythematosus, Sjogren's syndrome pericardial effusion, Anti nuclearantibodies, schirmer's test, pericardiocentesis