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Case Studies | Dermatology | Volume 12 Issue 12, December 2023 | Pages: 880 - 883 | India
Pyoderma Gangrenosum - A Case Report on Surgical Management
Abstract: Pyoderma gangrenosum is a rare dermatosis of unknown etiology and variable clinical presentation. Pathogenesis includes, neutrophil dysfunction, immune dysregulation and abnormal cytokine signalling by T cells and macrophages. This is the case of a 28 year old female diagnosed with pyoderma gangrenosum. Patient was referred from department of surgery in view of progressive non healing ulcers on dorsum of both feet. A skin biopsy performed from the edge ulcer showed features suggestive of pyoderma gangrenosum with dense dermo-epidermal neutrophilic infiltrate and perivascular lymphocytic infiltrate. Patient received immunosuppressive therapy for 1 month following which she underwent skin grafting. This report highlights the possibility of combining adequate immunosuppressive therapy with skin grafting for a better aesthetic outcome in these patients.
Keywords: Non healing ulcer, immunosuppression, split skin grafting
How to Cite?: Dr. Sanjana A S, Dr. Harshavardhan Gowda, Dr. Sushanth Gowda, Dr Sharavi Budanur, "Pyoderma Gangrenosum - A Case Report on Surgical Management", Volume 12 Issue 12, December 2023, International Journal of Science and Research (IJSR), Pages: 880-883, https://www.ijsr.net/getabstract.php?paperid=SR231209094244, DOI: https://dx.doi.org/10.21275/SR231209094244