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Case Studies | Neurology | India | Volume 12 Issue 10, October 2023

A Study on Etiological and Clinical Profile of Multiple Cranial Nerve Palsies

T. L. N. Geetha | N. Hemanth Kumar | N. V. S Chary

Abstract: Multiple cranial nerve palsies present a diagnostic challenge due to their diverse etiologies. This observational study aimed to investigate the underlying causes and clinical characteristics of patients with multiple cranial nerve palsies. A comprehensive assessment of 50 patients meeting inclusion criteria was done .Those with known causes of cranial nerve palsies were excluded. Data collected included detailed medical histories, comprehensive physical examinations, routine blood parameters, cerebrospinal fluid analysis, and neuroimaging studies. Among the patients analyzed, 62% were male, with an average age of 42.65 years. Vascular diseases were the predominant etiology, accounting for 36% of cases, Infections were the second most common cause (18%), with tuberculosis and bacterial meningitis identified as significant contributors. Guillain-Barr? Syndrome (GBS) and its variants constituted 12% of cases. Tumors (6%) and trauma (6%) were less frequent. Various combinations of cranial nerves were affected, with IX and X cranial nerves being the most frequently involved pair. Multiple cranial nerve palsies pose a complex diagnostic challenge, necessitating tailored clinical judgment for empiric therapy. This study highlights the diverse etiologies associated with multiple cranial nerve palsies useful in the evaluation and management of these challenging clinical presentations.

Keywords: cranial nerve, vascular, infections, tumors

Edition: Volume 12 Issue 10, October 2023,

Pages: 716 - 717