International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Neurology | Egypt | Volume 8 Issue 12, December 2019


Anxiety and Depression in Migraine Patients and Associated Risk Factors: A Cross - Sectional Study

Islam El Malky | Mohamed Moslem Hefny Mahmoud


Abstract: Introduction: Anxiety and depression are known to be comorbid with migraineurs in multiple studies. One study reported 8.6%?47.9% % prevalence of depression in migraine patients. The treatment of the comorbid anxiety and depression might have a good effect on the success in migraine treatment. Our study aims to find the prevalence of anxiety and depression in migraine patients and the possible predictors of this comorbidity. Methods: Patients with migraine diagnosis according to the international Classification of Headache Disorder 3 beta criteria were collected from the outpatient clinic of neurology. Clinical data, HADS (Hospital Anxiety and Depression Scale) and MIDAS Questionnaire (Migraine Disability Assessment test) were obtained from these patients. Results: The study population contained 118 patients, 108 patients (91.5 %) were female. The median of patients age was 32, range from 18 to 62 years. Rate of anxiety in this population was 44 patients (37%). After multivariate logistic regression, years of migraine complain and presence of aura were predictors of anxiety in migraine patients with p value 0.009 and 0.04, respectively and Odds ratio 1.108 [CI: 1.026-1.196] and 3.2 [CI: 9.71-1.05], respectively. Rate of depression was 37 patients (31.4 %). MDA score was the only variable, statistically significant with p-value 0.005. Conclusion: Anxiety and depression were obvious and with high-rate prevalence in our study group. Prolonged duration of migraine complain and migraine severity were predictors of anxiety and depression, respectively.


Keywords: Anxiety, depression, migraine


Edition: Volume 8 Issue 12, December 2019,


Pages: 1986 - 1988


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