Association of Degranulated Mast Cell Count with Burning Sensation of Oral Cavity in Oral Submucous Fibrosis

Dr Sabu Paul, Dr Pramod P Mathews

Abstract: Aim: To assess the possible role of degranulated mast cell count in oral submucous fibrosis patients with burning sensation. Materials and methods: The degranulated mast cell count was performed with microscope fitted with a calibrated mechanical stage in the histologically diagnosed specimens of oral submucous fibrosis. It was compared with burning sensation recorded using a self assessment descriptive rating. Statistics: ANOVA was used to test the equality of means between degranulated mast cell count and burning sensation. Results: Degranulated mast cell count showed a significant increase in early cases of oral submucous fibrosis along with the burning sensation. The difference was found to be statistically significant but insignificant in advanced cases. Conclusion: The increased degranulated mast cell count has a profound effect on the burning sensation experienced in oral submucous fibrosis especially in early cases.

Keywords: degranulated mast cell count, burning sensation, oral submucous fibrosis

How to Cite?: Dr Sabu Paul, Dr Pramod P Mathews, "Association of Degranulated Mast Cell Count with Burning Sensation of Oral Cavity in Oral Submucous Fibrosis", Volume 6 Issue 6, June 2017, International Journal of Science and Research (IJSR), Pages: 2845-2847, https://www.ijsr.net/getabstract.php?paperid=SR17716155445, DOI: https://dx.doi.org/10.21275/SR17716155445