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Research Paper | Biomedical Sciences | Volume 15 Issue 4, April 2026 | Pages: 1818 - 1823 | India
Insect Immune System-Inspired Antiviral Strategies: A Conceptual Perspective with Special Emphasis on HIV/AIDS
Abstract: This study investigates insect immune system-inspired antiviral mechanisms as potential templates for innovative therapies against viral diseases, with emphasis on HIV/AIDS. Key mechanisms reviewed include antimicrobial peptides, lectins, the prophenoloxidase cascade, and autophagy-related antiviral defenses. Their possible antiviral relevance, delivery methods, and translational challenges, including toxicity, specificity, and engineering optimization are discussed. Emerging technologies such as CRISPR gene editing, nanoparticle encapsulation, and peptide engineering may facilitate adaptation of these mechanisms into realistic biomedical applications. Although largely conceptual and requiring comprehensive experimental validation, insect-inspired immunotherapeutic strategies represent a promising direction for future antiviral research and developments.
Keywords: HIV-1, insect immunity, antimicrobial peptides, lectins, prophenoloxidase cascade, autophagy, biomimetic antivirals, innate immunity, translational therapeutics
How to Cite?: Shrenika Singhal, "Insect Immune System-Inspired Antiviral Strategies: A Conceptual Perspective with Special Emphasis on HIV/AIDS", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 1818-1823, https://www.ijsr.net/getabstract.php?paperid=MR26426195859, DOI: https://dx.dx.doi.org/10.21275/MR26426195859