Visual Inspection with Acetic Acid and Lugol's Iodine for Early Detection of Cervical Lesions with Colposcopy and Histopathology Correlation

Dr. Ananya P, Dr. Saroja C Kamatar

Abstract: Cervical cancer remains a major public health concern in developing countries due to inadequate screening coverage. Visual inspection with acetic acid (VIA) and visual inspection with Lugol?s iodine (VILI) are simple, low-cost screening methods suitable for low-resource settings. This study aimed to evaluate the efficacy of VIA and VILI in detecting premalignant and malignant cervical lesions and to correlate findings with colposcopy and histopathology. A prospective cross-sectional study was conducted among 100 women attending the gynecology outpatient department. All participants underwent VIA and VILI followed by colposcopy. Cervical biopsy was performed in women with abnormal findings, and histopathology was considered the gold standard. Histopathology confirmed cervical lesions in 10% of cases. VIA and VILI demonstrated a sensitivity of 70%, specificity of 100%, positive predictive value of 100%, negative predictive value of 96.8%, and diagnostic accuracy of 97%. Colposcopy showed complete correlation with histopathology. VIA and VILI are effective screening tools with high specificity and acceptable sensitivity for early detection of cervical lesions.

Keywords: Cervical cancer screening, VIA, VILI, Colposcopy, Cervical intraepithelial neoplasia

How to Cite?: Dr. Ananya P, Dr. Saroja C Kamatar, "Visual Inspection with Acetic Acid and Lugol's Iodine for Early Detection of Cervical Lesions with Colposcopy and Histopathology Correlation", Volume 15 Issue 1, January 2026, International Journal of Science and Research (IJSR), Pages: 1170-1171, https://www.ijsr.net/getabstract.php?paperid=MR26119211636, DOI: https://dx.doi.org/10.21275/MR26119211636