Transdermal Drug Delivery of Nanoemulgel to Treat Skin Diseases

Sweety Verma

Abstract: The emergence of nanoemulgels represents a thoughtful leap in the field of topical drug delivery, especially when addressing the long-standing challenges posed by conventional ointments, creams, and gels. Unlike traditional methods that often struggle with poor penetration and inconsistent drug release, nanoemulgels offer a promising alternative by blending nanoemulsion technology with a gel-based matrix. This unique combination enhances skin permeability, facilitates controlled drug release, and allows for more targeted therapeutic action, particularly for dermatological treatments. It is evident that the incorporation of natural oils like oleic acid and emu oil not only improves drug absorption but also brings additional therapeutic benefits such as anti-inflammatory and antioxidant properties. That said, the formulation process is far from simple; the careful selection of surfactants, cosurfactants, and gelling agents is critical to balancing stability, efficacy, and skin compatibility. One cannot overlook the fact that nanoemulgels also present certain hurdles-variability in skin physiology, potential instability of nano-sized particles, and the complexity of maintaining a consistent formulation are just a few examples. This suggests that while the technology holds great promise, it requires meticulous design and rigorous testing to unlock its full clinical potential. Taking this further, the application of nanoemulgels in treating conditions like acne, alopecia, and other skin disorders could redefine how we approach transdermal drug delivery in the future. By refining formulation techniques and embracing the bio-friendly characteristics of nanoemulgels, the pharmaceutical and cosmetic industries may find themselves on the brink of a transformative shift in patient care.

Keywords: nanoemulgel, transdermal delivery, skin permeability, targeted therapy, controlled drug release

How to Cite?: Sweety Verma, "Transdermal Drug Delivery of Nanoemulgel to Treat Skin Diseases", Volume 14 Issue 7, July 2025, International Journal of Science and Research (IJSR), Pages: 1136-1140, https://www.ijsr.net/getabstract.php?paperid=MR25714122116, DOI: https://dx.doi.org/10.21275/MR25714122116