Thyroid Function in Newly Diagnosed Pulmonary Tuberculosis Patients Pre- and -Post Intensive Phase: A Study in a Tertiary Medical College in Eastern Uttar Pradesh

Samriddhi Jha, Rk Yadav, Ad Shukla, J Shukla

Abstract: The link between Tuberculosis and Thyroid Dysfunction is not well defined. In this prospective observational study conducted at SRNH Prayagraj from February 2023 to May 2024, the thyroid function status of 61 newly diagnosed patients of Pulmonary Tuberculosis was assessed.75.4% were found to have low free T3 levels. The free T4 and TSH levels were found to fall within the normal range for 77% and 65.6% of patients respectively. At the initiation of Anti ? Tubercular Therapy, 23% of patients possessed low s. TSH levels, and 11.5% possessed high s. TSH levels. The mean TSH at baseline was 2.37?4.71 ?IU/ml, which rose to 3.13 ? 4.44 ?IU/ml at the end of the 2 ? month Intensive Period. The rise in TSH at the end of two months suggests a transition from nonthyroidal illness syndrome hormone pattern to subclinical hypothyroidism.

Keywords: tuberculosis, thyroid disorders, nonthyroidal illness syndrome, subclinical hypothyroidism, hypothyroidism, hyperthyroidism, anti - tubercular therapy, pulmonary tuberculosis

How to Cite?: Samriddhi Jha, Rk Yadav, Ad Shukla, J Shukla, "Thyroid Function in Newly Diagnosed Pulmonary Tuberculosis Patients Pre- and -Post Intensive Phase: A Study in a Tertiary Medical College in Eastern Uttar Pradesh", Volume 13 Issue 10, October 2024, International Journal of Science and Research (IJSR), Pages: 746-750, https://www.ijsr.net/getabstract.php?paperid=MR241009175829, DOI: https://dx.doi.org/10.21275/MR241009175829