International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Case Studies | Paediatrics | India | Volume 12 Issue 5, May 2023


Case Study on Rare Disease: Central Hypothyroidism in Case of Pitutary Hypoplasia

Dr. Saurabh Prajapati [2] | Dr. Jignesh Makavana [2] | Dr Priti Patel | Dr Pinakini Tollawala


Abstract: Central hypothyroidism is defined as hypothyroidism due to insufficient stimulation by thyroid stimulating hormone (TSH) of an otherwise normal thyroid gland. It has an estimated prevalence of approximately 1 in 80, 000 to 1 in 120, 000. It can be secondary hypothyroidism (pituitary Hypoplasia) or tertiary hypothyroidism (hypothalamus) in origin. In children, it is usually caused by craniopharyngiomas or previous cranial irradiation for brain tumors or Pitutary Hypoplasia or hematological malignancies. In adults, it is usually due to pituitary macroadenomas, pituitary surgeries or post - irradiation.


Keywords: Central hypothyroidism, Pituitary Hypoplasia, Pitutary, Craniopharyngioma


Edition: Volume 12 Issue 5, May 2023,


Pages: 354 - 356


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