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Case Studies | Medicine | India | Volume 12 Issue 3, March 2023
An Observational Study on Complications and Outcome of Malaria in Intensive Care Unit of Rural Teritary Care Hospital
Dr. G. Kalyan Kumar | Dr. Dhananjaya P. E | Dr. Y. J Visweswara Reddy | Dr. Akarnath
Abstract: Background: Malaria is still a major worldwide health issue. Drug resistant strains of malaria keep spreading and now affect practically every country on the planet1, 2. The study was conducted to describe the complications and to determine outcome in malaria cases admitted to intensive care unit of a rural tertiary care hospital. Methods: All the study patients were assessed for the demographic and clinical presentation by the principal investigator using pre structured proforma. Detailed investigation reports were collected from study population like complete blood count, peripheral smear, serum lactate dehydrogenase, serum bilirubin levels, serum urea and creatinine, peripheral blood smear for malarial parasite and malarial antigen test. Data was analysed using Statistical Package for the Social Sciences (SPSS). Descriptive statistics, chi square test, p value and independent sample t - test were done appropriately. p - value <0.05 was considered statistically significant. Conclusion: The bulk of the cases in the current study were males and were in the age group of 31 to 40 years. Notably, peripheral smear for malaria parasite and malarial antigen tests, were used to confirm the diagnosis of malarial infection in 70% and 30% of cases, respectively. In terms of complications caused by malaria, 58 % of cases had one complication, followed by 26 % of cases with 3 complications, 12% of cases with 2 complications, and 4% of cases with 4 complications. In this study, all patients were treated with Artesunate, doxycycline resulting in 100% recovery. Plasmodium falciparum was found to have varied course of illness ranging from single complication in 46% of patients to all four complications in 4% of patients and Plasmodium falciparum was always one of the causative organisms among the mixed parasitic infections. Hence, all cases of malaria with Plasmodium falciparum or multiple parasite infections needs to be identified early and treatment should be started promptly.
Keywords: Malaria, Plasmodium, Complications, Icu
Edition: Volume 12 Issue 3, March 2023,
Pages: 934 - 937