International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Case Studies | Medical Science | India | Volume 11 Issue 12, December 2022


Dyke-Davidoff-Masson Syndrome: A Rare Cause for Epilepsy - A Case Report

Dr. Ziddi Linggi


Abstract: Introduction: Dyke-Davidoff-Masson Syndrome [DDMS} refers to atrophy or hypoplasia of one cerebral hemisphere which is usually due to an insult on a developing brain in fetal or childhood period. Case Details: Here we report a case of 25 years old male presented with multiple episodes of generalized tonic clonic seizure. He was having similar episodes since last 10 years and was on antiepileptic medication irregularly. Patient had history of developmental delay and weakness of right upper and lower limb since early childhood. On physical examination patient had mild weakness in his right upper limb and lower limb and plantar reflex was extensor in right side. Laboratory data revealed no other abnormality. EEG was also normal. MRI of brain revealed left cerebral hemiatrophy and other features suggestive of DDMS. Diagnosis of Dyke-Davidoff-Masson syndrome was made and patient was started on levetiracetam and sodium valproate. Discussion: Dyke-Davidoff-Masson syndrome commonly presents with recurrent seizures, contralateral hemiplegia, facial asymmetry and mental retardation. This case highlights the importance of keeping DDMS as a differential diagnosis while evaluating a patient with seizure.


Keywords: Dyke-Davidoff-Masson Syndrome, cerebral hemiatrophy, calvarian thickening, osseus hypertrophy, hemispherectomy


Edition: Volume 11 Issue 12, December 2022,


Pages: 1169 - 1171


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