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Case Studies | Medicine Science | India | Volume 7 Issue 1, January 2018
A Case of Unusual Presentation of Takayasus Arteritis with Rheumatic Heart Disease
Dr. Viral Patel | Dr Kamal Pathak | Dr AlpeshVadher
Abstract: Takayasu & #039, s arteritis is a chronic inflammatory disease of the large and medium-sized arteries. It commonly involves the aorta with its branches and the pulmonary arteries. Clinically, pulsations were absent in the involved vessels- most commonly in the subclavian artery followed by common carotid and abdominal aorta, renal artery in majority of cases. The high prevalence rates of the disease is reported from Asian countries especially in Japan, India, Korea, and Thailand We present a 26 yrs. married female presenting with complaints of dyspnea, Paroxysmal nocturnal dyspnoea and a pitting oedema over both legs since 8 months at the time of presentation. She had a past history of hemiparesis on right side about a year back which completely recovered over 4-6 hrs. On obstetrics history she had multiple spontaneous abortions (n=3) in third trimester with a preterm delivery 6 months back. On examination all pulse on right side were absent barring weaker, low volumed femoral and carotid arteries. High blood pressure (200+10 and 100+10) was recorded in left brachial artery. Cardiac examination showed systolic murmur in all 4 areas. On investigation, all routine investigations were normal except a raised ESR (104).2D echo showed severe MR/TR/PAH and moderate MS/AR (probably of a rheumatic origin). To substantiate the diagnosis of a Antiphospholipid syndrome, APLA and ANA tests were done which were negative. A CT angiography of aortic root, its branches and abdominal aorta documenting occlusions of right subclavian artery, abdominal aorta, right femoral artery and bilateral renal artery. The relative lees frequently seen combination of Rheumatic heart disease in the face of a Takayasus arteritis is presented hereby for its uncommon occurrence.
Keywords: Takayasus arteritis, Rheumatic heart disease, Anti-phospholipid antibody, Anti Nuclear antibody
Edition: Volume 7 Issue 1, January 2018,
Pages: 1707 - 1708