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Original Research | Urology | Volume 15 Issue 7, July 2026 | Pages: 773 - 776 | India
Prospective Study on Outcome of Medical Expulsive Therapy in Ureteric Calculi
Abstract: Urolithiasis represents a highly prevalent and clinically challenging urological disorder causing severe morbidity and operational strains on healthcare systems globally. Medical Expulsive Therapy (MET) serves as an effective, non-invasive intermediate strategy to facilitate spontaneous stone clearance and minimize immediate endourological surgery loads. This prospective observational clinical investigation evaluated 237 adult subjects presenting with a single unilateral, uncomplicated ureteric stone measuring 10 mm or less within a high-volume tertiary hospital in Maharashtra, India. All participants received a standardized conservative regimen consisting of oral tamsulosin 0.4 mg once daily combined with supportive analgesia (diclofenac) for a maximum duration of 4 weeks. Weekly follow-up evaluations tracked symptom relief, medication adherence, side-effect profiles, and radiological clearance using targeted ultrasonography (USG), plain X-ray, or non-contrast computed tomography (NCCT) imaging. The overall successful stone expulsion rate was 78.48% (186 out of 237 patients), with a mean duration to expulsion of 10.90 ? 5.03 days. Active endourological surgical conversion (predominantly ureteroscopy with holmium laser lithotripsy) was required in 18.14% of cases due to persistent severe colic or tracking complications. Distal/lower third stone location was identified as the single strongest categorical predictor of clearance, yielding an 83.66% success rate (p = 0.002). Furthermore, successful passage correlated significantly with a smaller baseline mean stone diameter (6.17 ? 1.56 mm vs. 6.66 ? 1.44 mm, p = 0.037). Tamsulosin-based MET is highly efficacious, safe, and easily tolerated, modernizing conservative stone management and optimizing operating theater caseload dynamics in public healthcare systems.
Keywords: Tamsulosin, Ureteric Colic, Predictors of Spontaneous Passage, Outpatient Conservative Management
How to Cite?: Dr. Sushant Ganesh Gaonkar, Dr. Dnyaneshwar Gopinathrao Panchal, Dr. Meghraj Chawada, "Prospective Study on Outcome of Medical Expulsive Therapy in Ureteric Calculi", Volume 15 Issue 7, July 2026, International Journal of Science and Research (IJSR), Pages: 773-776, https://www.ijsr.net/getabstract.php?paperid=SR26709202515, DOI: https://dx.doi.org/10.21275/SR26709202515