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Research Paper | Microbiology | Volume 15 Issue 5, May 2026 | Pages: 1800 - 1811 | India
A Comparative Study on Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) in Nosocomial Infection
Abstract: Aim: To compare the prevalence, clinical characteristics, antibiotic resistance patterns, and outcomes of nosocomial infections caused by Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA). Objectives: 1) To determine the prevalence of MRSA and MSSA among patients with nosocomial infections in a healthcare setting. 2) To compare the clinical presentation and risk factors associated with MRSA and MSSA infections. 3) To evaluate the antibiotic susceptibility patterns of MRSA and MSSA isolates using standard laboratory methods. 4) To assess patient outcomes including duration of hospital stay, morbidity, and mortality related to MRSA and MSSA infections. 5) To analyse the infection control implications and suggest preventive strategies based on the findings. Result: A total of 52 MRSA and 48 MSSA cases were analysed. The average age of patients with MRSA was 57.6 years, slightly higher than the MSSA group, which had an average age of 54.2 years; however, the difference was not statistically significant (p=0.356). Gender distribution was relatively balanced in both groups, with a male-to-female ratio of 25:27 in MRSA and 24:24 in MSSA (p=0.85), indicating no significant difference. Conclusion: The findings suggest that methicillin resistance does not independently predict worse patient outcomes when proper management strategies, including early detection and tailored antibiotic therapy, are employed.
Keywords: nosocomial infections, MRSA, MSSA, antibiotic resistance, patient outcomes
How to Cite?: Upasana, Aradhana Singh, Akshita Upadhyaya, "A Comparative Study on Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) in Nosocomial Infection", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 1800-1811, https://www.ijsr.net/getabstract.php?paperid=SR26527165328, DOI: https://dx.dx.doi.org/10.21275/SR26527165328