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Comparative Study | Ophthalmology | Volume 15 Issue 5, May 2026 | Pages: 1582 - 1588 | India
Comparative Corneal Endothelial Cell Changes Following Different Cataract Surgical Modalities in Diabetic and Non-Diabetic Patients
Abstract: This prospective observational study assessed and compared corneal endothelial changes following phacoemulsification and manual small-incision cataract surgery (SICS) in diabetic and non-diabetic patients. A total of 120 eyes were included, comprising 60 diabetic and 60 non-diabetic patients, divided into four groups of 30 each. Patients aged above 40 years with grade 1?3 cataract according to the Lens Opacities Classification System III (LOCS III) underwent uneventful phacoemulsification or manual SICS. Corneal endothelial parameters were evaluated using the TOPCON SP-1P noncontact specular microscope with pachymeter one day preoperatively and one month postoperatively. Postoperative ECD showed a reduction in all groups, which was statistically significant in Groups A and B. CCT increased in all groups, with significant changes observed in Groups A, B, and D. Hexagonality decreased across all groups, reaching statistical significance in Groups B and D, while CV increased in all groups without statistical significance,When comparing the preoperative measurements with the 1-month follow-up, significant differences were observed across all groups, but no significant inter-group differences were found for any parameter. The study concludes that endothelial cell loss is comparable between phacoemulsification and SICS irrespective of diabetic status, indicating that SICS provides similar endothelial safety while remaining as a cost-effective alternative.
Keywords: Conventional Phacoemulsification, Manual Small Incision Cataract Surgery, Central Corneal Thickness, Endothelial Cell Loss, Diabetic status
How to Cite?: Dr. Orsu Divya Devi, Dr. Prajakta Paritekar, "Comparative Corneal Endothelial Cell Changes Following Different Cataract Surgical Modalities in Diabetic and Non-Diabetic Patients", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 1582-1588, https://www.ijsr.net/getabstract.php?paperid=SR26524142730, DOI: https://dx.dx.doi.org/10.21275/SR26524142730