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Case Studies | Histopathology | Volume 15 Issue 4, April 2026 | Pages: 627 - 629 | India
Lipoleiomyoma: An Uncommon Tumor with Diverse Presentations
Abstract: Uterine lipoleiomyoma is an uncommon benign tumor composed of smooth muscle and mature fat cells, usually identified in women after menopause, though it may occasionally appear in younger patients. Two contrasting clinical presentations are described, one in an older woman with mild symptoms and another in a younger patient with a large abdominal mass and long standing discomfort. Imaging in both situations suggested a fat containing uterine lesion, yet the final clarity came only after histopathological examination, which showed a mixture of adipocytes and smooth muscle without atypia, necrosis, or increased mitotic activity. What stands out here is how easily such lesions can be mistaken for more aggressive conditions, especially when size and symptoms vary widely. The discussion moves through possible origins, including metabolic and hormonal influences, while also touching on the idea of metaplastic change within the myometrium. Clinical features often remain subtle, which makes incidental detection fairly common, but larger tumors can lead to pressure related symptoms. Management tends to follow conventional approaches used for leiomyomas, with surgery considered when symptoms demand it. Careful microscopic assessment remains central, as it helps separate this benign entity from malignancies such as liposarcoma. Awareness of this rare variant becomes important in routine practice, particularly when radiological findings raise suspicion of fat containing pelvic masses, ensuring that patients are not exposed to unnecessary concern or overtreatment.
Keywords: uterine lipoleiomyoma, benign uterine tumor, adipocytes and smooth muscle, histopathological diagnosis, fat containing pelvic lesion
How to Cite?: Dr. Shanmugapriya Selvam, Dr. Vimal Mourouguessine, Dr. Thara Keloth, Dr. Abinizha Satchidanandan, "Lipoleiomyoma: An Uncommon Tumor with Diverse Presentations", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 627-629, https://www.ijsr.net/getabstract.php?paperid=SR26405195849, DOI: https://dx.dx.doi.org/10.21275/SR26405195849