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Research Paper | Medical Microbiology | Volume 15 Issue 4, April 2026 | Pages: 300 - 304 | India
Antivirulence Potential of Betel Leaves (Piper betle L.) in Combating Antimicrobial Resistance
Abstract: The global rise in antimicrobial resistance (AMR) has necessitated the exploration of alternative therapeutic strategies. Betel leaves (Piper betle L.), a traditional medicinal plant widely used in Asian cultures, have demonstrated promising antimicrobial and antivirulence properties. This paper reviews the phytochemical composition of betel leaves and examines their potential role in inhibiting virulence factors such as biofilm formation, quorum sensing, and toxin production in pathogenic microorganisms. Drawing from existing in vitro and in vivo studies, this research highlights the therapeutic relevance of natural antivirulence agents in addressing AMR while minimizing selective pressure for resistance development.
Keywords: Piper betle L., antimicrobial resistance, antivirulence, biofilm inhibition, quorum sensing, phytochemicals
How to Cite?: Hitesh Gurav, Shristi Mishra, "Antivirulence Potential of Betel Leaves (Piper betle L.) in Combating Antimicrobial Resistance", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 300-304, https://www.ijsr.net/getabstract.php?paperid=SR26403171703, DOI: https://dx.dx.doi.org/10.21275/SR26403171703