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Book Review | Health and Medical Sciences | Volume 15 Issue 4, April 2026 | Pages: 76 - 79 | India
A Comprehensive Conceptual Review on the Role of Ayurveda in the Management of Khalitya (Alopecia)
Abstract: Khalitya (Alopecia) is a prevalent dermatological concern with significant psychosocial implications. While modern medicine focuses on localized androgenetic and autoimmune pathways. In the contemporary era, hair loss or Khalitya has emerged as a significant psychosocial concern affecting global populations. Ayurveda categorizes Khalitya under Shiroroga (diseases of the head) or Kshudra Roga (minor diseases), primarily driven by the vitiation of Pitta and Vata Doshas in the hair follicles. This review synthesizes classical Ayurvedic perspectives with modern pathophysiology, exploring the efficacy of Shaman (palliative) and Shodhan (purificative) therapies. This review suggests that a personalized Ayurvedic approach-comprising Nasya, Siro-abhyanga, and Lepa- offers a holistic alternative to conventional treatment. Ayurveda offers a systemic perspective, categorizing Khalitya as a Dhatu-Pradoshaja Vikara (tissue-level disorder). This review synthesizes classical Ayurvedic pathogenesis (Samprapti) with modern molecular markers, specifically the Wnt/β-catenin and HPA axes. We propose a multi-modal therapeutic framework involving Sodhana (purification), Nasya (nasal drug delivery), and Keshya Rasayana (hair-rejuvenating) therapies. This conceptual model provides a scientifically rigorous basis for integrative trichology. This review examines the role of Ayurveda in the management of Khalitya (alopecia), a condition with significant psychosocial impact. It integrates classical Ayurvedic concepts of dosha imbalance and dhatu pathology with contemporary biological mechanisms, including inflammatory pathways and Wnt/β-catenin signaling. A structured literature search was conducted across major databases from 2010 to 2026 to identify relevant clinical and conceptual studies. The findings highlight the potential of multimodal Ayurvedic interventions such as Shodhana, Nasya, and Rasayana therapies in promoting scalp health and modulating systemic factors. Evidence suggests these approaches may influence neuroendocrine regulation and follicular dynamics. The review proposes an integrative framework linking traditional principles with molecular correlates, supporting Ayurveda as a complementary strategy for alopecia management.
Keywords: Alopecia Areata, Androgenetic Alopecia, Ayurvedic Therapy, Trichology, Hair Regrowth, Wnt Signaling, HPA Axis
How to Cite?: Dr. Ashish C. Zanwar, Dr. Vaibhav P Jaybhaye, "A Comprehensive Conceptual Review on the Role of Ayurveda in the Management of Khalitya (Alopecia)", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 76-79, https://www.ijsr.net/getabstract.php?paperid=SR26401161017, DOI: https://dx.dx.doi.org/10.21275/SR26401161017