Mycosis Fungoides in Skin Nodule
Abstract: Aim: To highlight the cytological features of mycosis fungoides and evaluate the diagnostic utility of fine-needle aspiration cytology (FNAC) in suspected cases. Objectives: To describe the FNAC findings in two clinically suspected cases of mycosis fungoides and emphasize the importance of cytology supported by immunohistochemistry in early diagnosis. Discussion: Mycosis fungoides is the most common primary cutaneous T-cell lymphoma but remains diagnostically challenging on cytology due to its rarity and morphological variability. FNAC smears in both cases showed atypical medium-to-large lymphoid cells with dense chromatin, irregular nuclear contours, and prominent nucleoli. Immunohistochemistry revealed positivity for CD3 and CD45, confirming T-cell lineage. Awareness of these cytomorphological features, along with clinical correlation, is crucial to avoid misdiagnosis. Early recognition on FNAC can facilitate timely management and improve patient outcomes.
Keywords: Mycosis fungoides, FNAC, Cutaneous T-cell lymphoma, Cytology, Immunohistochemistry
How to Cite?: Dr. Osho Vishwa Mohan, "Mycosis Fungoides in Skin Nodule", Volume 15 Issue 2, February 2026, International Journal of Science and Research (IJSR), Pages: 616-617, https://www.ijsr.net/getabstract.php?paperid=SR26209105752, DOI: https://dx.doi.org/10.21275/SR26209105752