A Systematic Review of Magnoflorine: Chemical Structure, Pharmacological Properties, Biological Activities, and Therapeutic Potential
Abstract: Magnoflorine is a plant-derived quaternary aporphine alkaloid found in several families of medicinal plants. Recent studies have shown that it possesses broad pharmacological potential, including anti-inflammatory, antimicrobial, antidiabetic, antihypertensive, and neuroprotective effects. It has also been linked to benefits in lifestyle-related disorders such as cancer, obesity, diabetes, dementia, and depression. Experimental studies highlighted its strong antioxidant activity, demonstrated through DPPH, ABTS, and DMPD radical-scavenging assays, as well as metal-ion reduction tests. Magnoflorine demonstrated effective DPPH radical scavenging with an IC?? of 10.58 µg/mL, comparable or superior to standard antioxidants like BHA, BHT, and ?-tocopherol. Additionally, it inhibits key enzymes such as acetylcholinesterase, butyrylcholinesterase, and ?-glycosidase at very low concentrations, suggesting potential roles in managing diabetes, Alzheimer's disease, and glaucoma. Overall, magnoflorine emerges as a promising natural compound for future therapeutic and drug development applications.
Keywords: Magnoflorine, Quaternary Aporphine Alkaloid, Antioxidant activity, Enzyme inhibition, Antidiabetic, In-Vitro studies
How to Cite?: Saurav Kumar Karwate, Rakesh Choure, "A Systematic Review of Magnoflorine: Chemical Structure, Pharmacological Properties, Biological Activities, and Therapeutic Potential", Volume 15 Issue 1, January 2026, International Journal of Science and Research (IJSR), Pages: 1697-1700, https://www.ijsr.net/getabstract.php?paperid=SR26129110431, DOI: https://dx.doi.org/10.21275/SR26129110431