Literature Review: Zinner Syndrome

Dr Sagar B Joshi, Niharika N Singh

Abstract: Zinner Syndrome (ZS) is a rare congenital anomaly defined by a triad: unilateral renal agenesis, an ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. First reported by Zinner in 1914, the syndrome is considered the male equivalent of Mayer-Rokitansky-K?ster-Hauser (MRKH) syndrome in females. Due to its nonspecific presentation and low prevalence, it is often underdiagnosed. This review presents a comprehensive overview of the embryological basis, clinical manifestations, diagnostic approaches, and current management options for Zinner Syndrome, while also addressing recent advances and the impact on fertility.

Keywords: Wolffian duct abnormality, Renal agenesis, Seminal vesicle cyst

How to Cite?: Dr Sagar B Joshi, Niharika N Singh, "Literature Review: Zinner Syndrome", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 416-418, https://www.ijsr.net/getabstract.php?paperid=SR25809001547, DOI: https://dx.doi.org/10.21275/SR25809001547