Green-Synthesized Zinc Oxide Nanoparticles Enhance Tail Fin Regeneration in Gambusia affinis

Pradnya Sunil Bapte, Dhanashree Kailas Chavhan, Pallavi Balasaheb Kangane, Seema Sachin Borgave

Abstract: The present study explores the regenerative effects of green-synthesized zinc oxide nanoparticles (ZnO NPs), derived from pomegranate leaf extract, on tail fin regeneration in Gambusia affinis. Fish were subjected to tail fin amputation and exposed to varying concentrations (10, 20, and 30 ?g/mL) of ZnO NPs over a 96-hour period. At lower concentrations, ZnO NPs enhanced regeneration, with 10 ?g/mL showing the most sustained effect. However, higher doses initially accelerated regrowth but later hindered the process, likely due to cytotoxic effects. The findings underscore the biomedical potential of plant-mediated ZnO NPs in tissue regeneration, while also emphasizing the importance of optimal dosing.

Keywords: green synthesis, Gambusia affinis, nanotoxicity, tail fin regeneration, zinc oxide nanoparticles

How to Cite?: Pradnya Sunil Bapte, Dhanashree Kailas Chavhan, Pallavi Balasaheb Kangane, Seema Sachin Borgave, "Green-Synthesized Zinc Oxide Nanoparticles Enhance Tail Fin Regeneration in Gambusia affinis", Volume 14 Issue 7, July 2025, International Journal of Science and Research (IJSR), Pages: 1478-1482, https://www.ijsr.net/getabstract.php?paperid=SR25723160519, DOI: https://dx.doi.org/10.21275/SR25723160519