Ocular Manifestations in Reactions in Leprosy Patients

Priyalika Agarwal, Alka Gupta, Lokesh Kumar Singh, Jaishree Dwivedi, Amarjeet Singh

Abstract: Purpose: To evaluate the spectrum and prevalence of ocular manifestations in patients with reactional states of Hansen?s disease (leprosy) and to assess associated visual outcomes. Methods: A cross - sectional observational study was conducted on 45 patients with reactional leprosy at LLRM Medical College, Meerut. Ocular examinations included visual acuity, slit - lamp biomicroscopy, corneal sensation testing, ocular surface staining, and fundus evaluation. Results: Ocular manifestations were present in 66.7% of patients. The most affected structures included the cornea (80%), lens (50%), and adnexa (madarosis 56.6%). Patients who discontinued treatment showed the highest rates of blindness (11%) and severe visual impairment (18%). Complete adherence to multidrug therapy (MDT) correlated with preserved vision in all cases. Conclusion: Ocular involvement in leprosy is frequent and significantly impacts visual morbidity, particularly during reactional episodes. Early identification, interdisciplinary care, and sustained therapy are pivotal to preserving visual outcomes.

Keywords: Leprosy, Ocular Manifestations, Reactional States, Visual Impairment, Multidrug Therapy

How to Cite?: Priyalika Agarwal, Alka Gupta, Lokesh Kumar Singh, Jaishree Dwivedi, Amarjeet Singh, "Ocular Manifestations in Reactions in Leprosy Patients", Volume 14 Issue 5, May 2025, International Journal of Science and Research (IJSR), Pages: 947-949, https://www.ijsr.net/getabstract.php?paperid=SR25514191238, DOI: https://dx.doi.org/10.21275/SR25514191238