Gastrointestinal Stromal Tumor: A Case Report with Risk Assessment

Harikrishna Akurathi, Dr. Vaddatti Tejeswini, P Lakshmi Pranathi, Dr. I V Renuka

Abstract: Background: Gastrointestinal stromal tumors (GIST) are rare tumors of the gastrointestinal tract arising from the intestinal cells of Cajal. The most common site of origin is the stomach. Case: Here we report a case of gastro intestinal stromal tumor in a 63 years old female who came with chief complaint of pain in abdomen and swelling in left ileac fossa. The radiological diagnosis was a gastro intestinal stromal tumor. Trucut biopsy was taken which revealed benign gastrointestinal stromal tumor. Diagnosis of GIST is made histologically and immunohistochemically. Immunohistochemically, the diagnosis of GISTs is made with CD117 positivity. The gold standard treatment is surgical resection. In patients with locally advanced tumors or metastasis, adjuvant targeted therapy using tyrosine kinase inhibitors (Imatinib) can be used. Conclusion: The histopathological diagnosis of gastrointestinal stromal tumor is required for risk assessment of the tumor and its prognosis.

Keywords: Gastrointestinal stromal tumor, CD117, Immunohistochemistry, surgical resection, imatinib therapy, histopathological diagnosis

How to Cite?: Harikrishna Akurathi, Dr. Vaddatti Tejeswini, P Lakshmi Pranathi, Dr. I V Renuka, "Gastrointestinal Stromal Tumor: A Case Report with Risk Assessment", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 2363-2365, https://www.ijsr.net/getabstract.php?paperid=SR25407101021, DOI: https://dx.doi.org/10.21275/SR25407101021