Nicolau Syndrome Presenting as an Ischemic Upper Limb - Management & Functional Outcome

Dr. Radhika Yadav, Dr. Rupali Rastogi, Dr. Ruchi Tyagi, Dr. Shashank Mishra

Abstract: Nicolau syndrome condition also known as embolia cutis medicomentosa, could be an uncommon complication characterized by tissue ischemia & gangrene that occurs after the infusion of drugs. The precise pathogenesis is questionable, but there are a few theories, counting coordinate harm to the end supply route and cytotoxic impacts of the medicate. Extreme torment within the quick post - injection period and purplish discoloration of the skin with a reticulate pigmentary design is characteristic of this disorder. In adverse conditions, it may cause tissue rot and compartment disorder. Determination is basically clinical, and there's no standard treatment for the illness. In this, we present a case with the conclusion of Nicolau Syndrome displaying with appendage ischemia due to diclofenac infusion; which could be an uncommon event.

Keywords: Nicolau syndrome, Tissue Ischemia, Gangrene, Diclofenac infusion, Appendage Ischemia

How to Cite?: Dr. Radhika Yadav, Dr. Rupali Rastogi, Dr. Ruchi Tyagi, Dr. Shashank Mishra, "Nicolau Syndrome Presenting as an Ischemic Upper Limb - Management & Functional Outcome", Volume 14 Issue 4, April 2025, International Journal of Science and Research (IJSR), Pages: 328-330, https://www.ijsr.net/getabstract.php?paperid=SR25402233326, DOI: https://dx.doi.org/10.21275/SR25402233326