Carbamazepine Induced Stevens Johnson Syndrome - A Case Report

Dr. Somdatta Ghosh, Dr. Supreeti Biswas Mondal

Abstract: Carbamazepine is considered to be the first-line treatment for trigeminal neuralgia. It may rarely lead to complications like Stevens Johnson syndrome (SJS). Initially thought to be a dose-independent, idiosyncratic, unpredictable adverse event specific to an individual, SJS is now considered a delayed hypersensitivity immune reaction involving human leukocyte antigen (HLA) alleles specific for carbamazepine and other drugs in defined populations. In the present case, carbamazepine was immediately withdrawn upon diagnosis of SJS and the patient was managed conservatively using corticosteroids and oral anti-histaminic agents.

Keywords: Carbamazepine, Stevens Johnson Syndrome, Human Leukocyte Antigen

How to Cite?: Dr. Somdatta Ghosh, Dr. Supreeti Biswas Mondal, "Carbamazepine Induced Stevens Johnson Syndrome - A Case Report", Volume 14 Issue 2, February 2025, International Journal of Science and Research (IJSR), Pages: 416-418, https://www.ijsr.net/getabstract.php?paperid=SR25206094227, DOI: https://dx.doi.org/10.21275/SR25206094227