Wegener's Granulomatosis Presenting with Spontaneous Intestinal Perforation: A Diagnostic Dilemma During the COVID-19 Pandemic
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Case Studies | General Surgery | India | Volume 14 Issue 1, January 2025 | Popularity: 5.6 / 10


     

Wegener's Granulomatosis Presenting with Spontaneous Intestinal Perforation: A Diagnostic Dilemma During the COVID-19 Pandemic

Uma Perumal, Chirag Panara, Samiran Nundy, Samrat Ray, Atul Kakar


Abstract: A 25-year-old woman presented with acute abdominal pain, preceded by fever and polyarthralgia. Emergency laparotomy revealed ileal perforation, necessitating small bowel resection. Postoperatively, persistent respiratory symptoms and prior constitutional complaints led to reevaluation, revealing vasculitis, likely granulomatosis with polyangiitis (Wegener?s granulomatosis). Pulse steroid therapy resulted in significant improvement, with a kidney biopsy and rituximab therapy planned. This case highlights the diagnostic challenges during the COVID-19 pandemic, where gastrointestinal symptoms and high false-negative RT-PCR results contributed to delayed diagnosis. [1] It underscores the importance of maintaining a broad differential diagnosis to avoid critical delays in managing non-COVID-related diseases.


Keywords: Wegener's granulomatosis, granulomatosis with polyangiitis, intestinal perforation, vasculitis, COVID-19


Edition: Volume 14 Issue 1, January 2025


Pages: 1161 - 1164


DOI: https://www.doi.org/10.21275/SR25125200335



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Uma Perumal, Chirag Panara, Samiran Nundy, Samrat Ray, Atul Kakar, "Wegener's Granulomatosis Presenting with Spontaneous Intestinal Perforation: A Diagnostic Dilemma During the COVID-19 Pandemic", International Journal of Science and Research (IJSR), Volume 14 Issue 1, January 2025, pp. 1161-1164, https://www.ijsr.net/getabstract.php?paperid=SR25125200335, DOI: https://www.doi.org/10.21275/SR25125200335