Shared Immunological Pathways in Psoriasis and Vitiligo: Insights from a Case Study

Dr. Gulshant Panesar

Abstract: Psoriasis is a chronic inflammatory skin disease characterized by well demarcated erythematous plaques covered with silvery white scales, present chiefly on extensors. Vitiligo is autoimmune disorder that causes patchy loss of skin pigmentation. In some cases the two disorders can be present concurrently. Very few case reports of co existing psoriasis and vitiligo are there in literature, though immunological pathways of both diseases overlap. We present a case of 36 year old male presenting with coexisting psoriasis and vitiligo. Most case reports cite development of psoriasis in preexisting vitiligo lesions whereas in our case, patient developed psoriasis long before the onset of vitiligo. Material and methods: 36 year old male presented to skin OPD with depigmented macules on lips, palms and soles since 3 years. He also had scaly erythematous plaques on extensors since 17 years which was diagnosed as Psoriasis and he was being treated for it. Diagnosis of psoriasis coexistent with vitiligo was made based on clinical examination and skin biopsy. Conclusion: Association of psoriasis with vitiligo has been described but very few cases are reported from India. The diseases can be present concurrently due to their pathogenesis involving inflammation and autoimmunity.

Keywords: Psoriasis, Vitiligo, Concurrent, Immunological

How to Cite?: Dr. Gulshant Panesar, "Shared Immunological Pathways in Psoriasis and Vitiligo: Insights from a Case Study", Volume 15 Issue 1, January 2026, International Journal of Science and Research (IJSR), Pages: 370-371, https://www.ijsr.net/getabstract.php?paperid=SR251229141806, DOI: https://dx.doi.org/10.21275/SR251229141806