Seroprevalence of Scrub Typhus among Pyrexia of Unknown Origin Patients: A Study from a Tertiary Care Hospital in Odisha

Dr. Debaprasad Mishra

Abstract: Scrub typhus is a crucial rickettsial infection caused by Orientia tsutsugamushi and a significant cause of acute undifferentiated febrile illness in India. Due to limited diagnostic facilities, the disease often remains underdiagnosed, leading to increased risk of morbidity and mortality. The present investigation was under taken in a Tertiary Care Hospital to assess the seroprevalence of scrub typhus and to compare the diagnostic performance of immunochromatographic test (ICT) with IgM ELISA. The study reported good correlation between ICT and ELISA. IgM ELISA demonstrated higher sensitivity (92.41%) and specificity (91.29%) compared to ICT. Investigation concluded that for Scrub typhus IgM ELISA remains a reliable diagnostic modality.

Keywords: Scrub typhus, Pyrexia of unknown origin, IgM ELISA, ICT, Orientia tsutsugamushi

How to Cite?: Dr. Debaprasad Mishra, "Seroprevalence of Scrub Typhus among Pyrexia of Unknown Origin Patients: A Study from a Tertiary Care Hospital in Odisha", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 1781-1782, https://www.ijsr.net/getabstract.php?paperid=SR251221144634, DOI: https://dx.doi.org/10.21275/SR251221144634