Flaccid Paralysis in Pregnancy Due to Autoimmune Etiology: A Rare Case and Multidisciplinary Management

Tintu S. R.

Abstract: Flaccid paralysis during pregnancy is an uncommon but potentially serious neurological condition that demands timely recognition and coordinated care. This article presents the case of a 24-year-old pregnant woman at 28 weeks of gestation who developed progressive weakness and numbness of the lower limbs, later involving the upper limbs and trunk, without any preceding trauma, infection, or toxin exposure. Clinical examination revealed reduced muscle power, absent deep tendon reflexes, and sensory impairment, while imaging and cerebrospinal fluid analysis supported the diagnosis of autoimmune-related flaccid paralysis with longitudinally extensive transverse myelitis. Management involved intensive monitoring, a multidisciplinary approach, and treatment with plasmapheresis and intravenous immunoglobulin, alongside comprehensive nursing care and close fetal surveillance. Gradual neurological improvement was observed, and the patient later delivered a healthy infant by cesarean section, followed by continued recovery in the postpartum period. This case highlights the importance of early diagnosis, vigilant supportive care, and coordinated obstetric and neurological management to achieve favorable maternal and fetal outcomes in rare neurological complications of pregnancy.

Keywords: Flaccid paralysis, pregnancy complications, autoimmune neurological disorder, transverse myelitis, multidisciplinary care

How to Cite?: Tintu S. R., "Flaccid Paralysis in Pregnancy Due to Autoimmune Etiology: A Rare Case and Multidisciplinary Management", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 1353-1354, https://www.ijsr.net/getabstract.php?paperid=SR251217200449, DOI: https://dx.doi.org/10.21275/SR251217200449