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Research Paper | Fashion and Textiles | Volume 14 Issue 11, November 2025 | Pages: 1994 - 1999 | United States
Photobiological Effects of LED Lamps in Nail Services: Risks and Safety Considerations
Abstract: The study aims to systematize and critically interpret the existing body of scientific data on the photobiological effects of UV/LED radiation to construct an integral, multilevel risk assessment. A systematic search and analytical processing of the literature were performed, covering in vitro experiments, physical-dosimetric measurements, clinical observations, and industry analytical reports. It was established that the emission of the lamps under consideration falls predominantly within the UVA range (320-400 nm), while irradiance varies between models by more than 26-fold (0,6-15,7 mW/cm?), which makes the reduction of risk assessment to exposure time alone methodologically untenable. In vitro data demonstrate the induction of reactive oxygen species, accompanied by genotoxic DNA damage (8-oxoguanine) and the formation of a specific C:G>A:T mutational signature associated with carcinogenesis. Clinical reports include cases of squamous cell carcinoma in individuals with prolonged use of UV lamps. Despite a likely low average population risk, the cumulative absorbed dose with regular operation of devices with high and unregulated variability of power output forms a significant genotoxic and carcinogenic risk for individual users, which is currently underestimated. The information presented in this work will be of interest to nail service specialists, dermatologists, and organizations responsible for public health and standardization.
Keywords: UVA radiation, LED lamps, nail service, photobiology, carcinogenic risk, DNA damage, squamous cell carcinoma, dosimetry, safety, keratinocytes
How to Cite?: Yefremova Natalia Olegovna, "Photobiological Effects of LED Lamps in Nail Services: Risks and Safety Considerations", Volume 14 Issue 11, November 2025, International Journal of Science and Research (IJSR), Pages: 1994-1999, https://www.ijsr.net/getabstract.php?paperid=SR251114073333, DOI: https://dx.doi.org/10.21275/SR251114073333