Diagnostic Accuracy of Hysteroscopy in Relation to Histopathology in Patients with Abnormal Uterine Bleeding at a Tertiary Care Centre

Dr Kanak Kumari, Dr. Payal Jain, Dr. Deepika Panwar, Dr. Preeti Agrawal

Abstract: Background: Abnormal uterine bleeding (AUB) significantly impacts women's health and requires accurate diagnosis to identify underlying pathologies. Hysteroscopy, a minimally invasive technique, allows direct visualisation of the uterine cavity and is often used alongside histopathological evaluation. This study aims to assess the diagnostic accuracy of hysteroscopy in comparison to histopathology in patients with abnormal uterine bleeding. Methods: This prospective observational study was conducted at American International Institute of Medical Sciences, Udaipur, over a period of 12 months. A total of 120 women aged 20?65 years with abnormal uterine bleeding underwent hysteroscopy followed by endometrial sampling for histopathological examination. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of hysteroscopy were calculated for different intrauterine abnormalities. Results: Hysteroscopy identified endometrial polyps in 30% of cases, submucosal fibroids in 25%, and hyperplasia in 8.3%. Histopathology confirmed these findings in 29.2%, 23.3%, and 12.5% of cases, respectively. The sensitivity, specificity, PPV and NPV for detecting endometrial polyps were 94.4%, 95.0%, 91.7%, and 97.4%, respectively. For submucosal fibroids, these values were 89.3%, 93.7%, 86.7%, and 95.0%, respectively. Hysteroscopy showed a 100% sensitivity and NPV for detecting malignancy. Conclusion: Hysteroscopy demonstrated high diagnostic accuracy for structural abnormalities in AUB, with excellent sensitivity and specificity for endometrial polyps and fibroids. However, its sensitivity for detecting hyperplasia was lower, highlighting the importance of histopathological confirmation. These findings support the use of hysteroscopy as a first-line diagnostic tool for AUB in tertiary care settings.

Keywords: Abnormal uterine bleeding, hysteroscopy, histopathology, diagnostic accuracy, endometrial abnormalities

How to Cite?: Dr Kanak Kumari, Dr. Payal Jain, Dr. Deepika Panwar, Dr. Preeti Agrawal, "Diagnostic Accuracy of Hysteroscopy in Relation to Histopathology in Patients with Abnormal Uterine Bleeding at a Tertiary Care Centre", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 310-315, https://www.ijsr.net/getabstract.php?paperid=SR251111131430, DOI: https://dx.doi.org/10.21275/SR251111131430