Audit-Based Actions to Reduce Wastage and Transfusion-Transmitted Infection (TTI) Positivity at a Hospital-Based Blood Center

Dr. Ramesh Yadav, Dr. Muskan Chaudhary, Dr Anshul Bansal

Abstract: Background: Blood wastage and transfusion-transmitted infection (TTI) positivity reflect the efficiency and quality of a blood center. Reducing discard rates through structured audits and corrective actions is key to improving transfusion safety. Aim: To evaluate the trends of blood component wastage and TTI positivity through audit-based quality improvement measures in a hospital-based blood center. Methods: A retrospective clinical audit was conducted at a tertiary care hospital blood center from July 2023 to December 2024 in three stages: baseline data collection, root-cause analysis, and implementation of corrective and preventive actions using the Plan-Do-Study-Act (PDSA) approach. Data were collected for four consecutive cycles. Key Performance Indicators (KPIs) studied were TTI positivity (HIV, HBsAg, HCV, Syphilis, Malaria) and blood component wastage. Results: TTI positivity remained low throughout the study, while wastage rates declined with each cycle. Mean TTI positivity (%): HIV 0.17 ± 0.03, HBsAg 0.33 ± 0.04, HCV 0.11 ± 0.02, Syphilis 0.33 ± 0.04, Malaria 0.02 ± 0.02. Mean component wastage (%): Whole Blood 0.01 ± 0.004, Platelets 0.07 ± 0.02, Total 0.08 ± 0.02. Conclusion: Regular audits with targeted corrective and preventive measures significantly reduce wastage and maintain infection control. Continuous monitoring ensures sustained quality improvement in transfusion services.

Keywords: Blood wastage, TTI positivity, Quality audit, PDSA cycle, Blood center

How to Cite?: Dr. Ramesh Yadav, Dr. Muskan Chaudhary, Dr Anshul Bansal, "Audit-Based Actions to Reduce Wastage and Transfusion-Transmitted Infection (TTI) Positivity at a Hospital-Based Blood Center", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 1271-1273, https://www.ijsr.net/getabstract.php?paperid=SR251029131656, DOI: https://dx.doi.org/10.21275/SR251029131656